Serious CBD Oil Side Effects Nobody Told You About
CBD oil — that magnificent, powerful phrase/product/cure that we have heard so much about. Everywhere you turn, there are praise and glory about its impact. However, rarely does one hear anything about the CBD oil side effects, even though they are extremely important.
The “bad boy” THC is to be partially blamed for this. The public has been focused on its effects for so long, even trying to ban cannabis entirely due to this psychoactive ingredient. That said, when CBD was discovered, people were inclined to believe cannabidiol is what makes cannabis such a powerful healer.
However, nothing is perfect, and neither is CBD. Contained in hemp oil or not, with or without some THC content, CBD oil comes with its fair share of downsides.
First, let’s take a quick look at what CBD is, and then you’ll find out everything there is to know about the negative side effects of CBD oil.
The Basics of CBD
What Is CBD?
CBD (cannabidiol) is just one of many cannabinoids in the cannabis plant. CBD structure remains absolutely the same whether we’re talking about CBD from hemp (Cannabis Sativa) or the ‘’regular cannabis” (Cannabis Indica).
There are over 100 cannabinoids within cannabis. These natural substances can bind to our own endocannabinoid system. This is why CBD is so efficient in the first place — our body recognizes it as a familiar substance.
Luckily for us, CBD research suggests new incredible health benefits every day.
What Is CBD Oil?
To better understand the CBD oil benefits and its effects, let’s explain what the oil actually represents.
There are two types of CBD oil:
- Pure CBD oil
- Full-spectrum CBD oil
The first one is guaranteed to have nothing else but CBD and carrier oil (olive, avocado, hemp seed oil, coconut oil, etc.). The latter comprises CBD, THC, and all the other cannabinoids you can find in a cannabis plant. Terpenes come into the picture as well.
CBD oil can be taken in various ways — as the oil itself and as a CBD oil-infused product (CBD gummies, creams, lotions, patches, pills, and so on).
Less and More Common CBD Side Effects
Similarly to any medicine, CBD oil comes with a (long) list of warnings. And just like it is the case with any other drugs, the side effects may or may not exhibit themselves. Regardless of the reason, the fact remains that some people will endure the adverse effects.
One of the biggest reasons for this is that we are all different and that our bodies react individually to a stimulant. In addition to this, there are some things we can influence to avoid the side effects of CBD and get the maximum of its good sides.
Here are the most common disadvantages of CBD usage!
Whereas it is usually THC that is praised for a cannabis treatment for insomnia, CBD can make you drowsy as well. This is usually the case if you take a higher CBD dose than recommended.
On the other hand, if you wish to avoid these CBD negative side effects, just take a smaller dose.
CBD is not cut out for a sensitive stomach or palate.
If you take CBD in the form of oil drops, you could feel sick. This is especially true if you take it on an empty stomach. The general rule of thumb applies here as well — take your medicine half an hour or an hour after a meal. Drink plenty of water afterward.
Due to its application, the CBD cream side effects will include some other states, such as tiredness but hardly ever nausea.
Appetite Boost or Loss
Depending on what you’re trying to achieve, this could be great for you. CBD oil products are very much praised for increasing appetite, particularly in cancer patients.
Moreover, CBD oil for anxiety and reduced anxiety levels usually encourage people to eat more. The appetite-boosting quality is mainly connected with full-spectrum CBD oil.
Tingling and Numbness
CBD oil side effects include tingling on the lips or all over your body, especially if you’ve applied CBD oil topically. On the one hand, this is nothing to worry about and the sensation should disappear soon enough (within minutes). Many find it enjoyable, too, and it’s definitely one of the reasons people opt to try out CBD-infused lubes.
On the other hand, extreme or prolonged tingling sensation or numbness could be a sign you’ve exposed yourself to a higher dose of THC, so make sure you only buy CBD oil, flowers, etc. from reliable suppliers.
CBD Oil Side Effects on Eyes
Besides causing eye redness as one of the most common side effects, people with glaucoma should avoid using CBD products. Based on the American Academy of Ophthalmology report from 2019, CBD oil can worsen the symptoms of glaucoma.
Namely, the researchers found out that CBD can raise the eye’s pressure by 18% four hours after applying CBD drops.
On the other hand, drops containing only THC can decrease the eye’s pressure by 30% within eight hours.
Since more research is needed on the subject, it’s not advisable to use CBD products to treat glaucoma.
Dry mouth is one of the second most common CBD oil side effects. Basically, it is the feeling as if someone filled your mouth with cotton balls. It usually occurs if you’re using oil drops.
The scientific experiment behind it suggests that CBD inhibits the endocannabinoid receptors in our brain, which are responsible for saliva production.
Luckily, dry mouth is only temporary and easily solved — just take a big glass of water after consuming CBD oil.
Smoking CBD Oil Causes Sore Throat
Smoking or vaping CBD oil can result in a sore throat and raspy voice. As you know, smoking blunts or CBD pre-rolls makes your mouth and throat dry because you inhale toxic chemicals together with the tar from the hot and dry air.
The severity of the throat irritation will depend on the type of cannabis you vaped or smoked and your tolerance to smoke.
On top of that, smoking CBD oil burns your throat, so if you want to avoid these problematic side effects, you should:
- Stay hydrated
- Avoid spicy foods
- Gargle with warm salty water
- Reduce the frequency of smoking/vaping
Other alternative methods that can help you with a sore throat include:
- Avoiding energy drinks and caffeine
- Licking lemon or honey
- Drinking herb tea with fruits
- Buying a vaporizer that will get rid of the stale, dry air in your home
- Smoking outside of your home
CBD Vape Oil Side Effects
Vaping CBD oil can cause the following side effects:
- Feeling drowsy
- Decreased appetite
- Fatigue, discomfort, lack of energy
To avoid these side effects, make sure you’re vaping CBD correctly. First of all, avoid additives like diacetyl and vitamin E acetate. Next, buy your CBD from reliable brands, and lastly, determine the correct dosage.
Diarrhea is one of the side effects of CBD oil in humans as well as their pets. Here are the two main reasons why you could be experiencing this symptom:
- As with any other medication, your body needs some time to adjust to it.
- Since CBD oil alters your appetite, you may have changed your regular eating habits. Your gut gets revolted against the smaller or bigger food intake.
After one or two weeks, the symptoms should stop. Your body will adjust to CBD and the new eating pattern. If you are already suffering from diabetes or a similar appetite/weight loss condition, be very careful about maintaining your goal weight.
CBD Oil for Sleep Side Effects
On the one hand, CBD oil will help you fall asleep faster. On the other hand, you may experience very realistic dreams during the first couple of nights. Even nightmares.
What happens is that CBD allows you to enter a deep sleep stage called N3, delta sleep, or slow-wave sleep. Luckily, you should be free of bad dreams after two days or as much as it takes your brain to adjust to the new substance.
CBD Oil Side Effects on Kidneys
There are some opposite opinions on this one. According to one study, cannabis is beneficial for patients with advanced chronic kidney disease (CKD). It helps them regulate the pain and exhibits no side issues.
Another research found that cannabis has an adverse effect, especially if it’s consumed via smoking. Patients were advised against medical marijuana, and CBD oil possibly could have the same effect.
What are the side effects of CBD for healthy people? Apparently, none. Those who did not suffer from kidney disease did not show any reduction in kidney functions while using cannabis.
Dizziness due to CBD oil typically occurs if one takes a higher dose than they should. The easiest way for this to happen is during vaping. It takes some skill to master it because it isn’t the same as smoking a joint.
Usually, people smoke concentrates rich in CBD, THC, and terpenes, so the “high” hits them rather unexpectedly.
To avoid side effects of vaping CBD, be moderate and careful about how you get your CBD vape oil. Dizziness could also be caused by low blood pressure.
Various studies have reported a link between cannabinoids and Parkinson’s, yet, we still don’t have enough evidence that shows it can be used as a potential treatment.
Parkinson’s patients are advised against using it if it interacts with some other medications because it can cause mood changes, diarrhea, and tiredness.
Keep in mind that if you use a too high dosage, it could even worsen the symptoms of the disease.
Grapefruit and CBD Oil Side Effects
Grapefruit and similar fruits contain certain substances that interact with CYP450 enzymes. In short, it prevents them from doing their job of dealing with the drugs we take.
If the enzymes are unable to do their part of breaking down the drugs in our bodies, the drug will end up in our liver, from where it will go into our bloodstream unprocessed. This means that you could end up with more drugs in your system than you are entitled to.
What about CBD tincture side effects? CBD behaves similarly, plus it interferes with more enzymes (CYP3A4 and CYP2D6) and increases the drug level even more.
Even after you quit using CBD oil, your body won’t be able to use the drug normally until a few days have passed.
In this respect, the side effects will also show if a person is taking antidepressants, antihistamines, benzodiazepines, and statins.
To prevent the triggers in this case, be wary of the grapefruit warning on medications. Otherwise, CBD will turn the low dose of your medicine into a high dose.
CBD Oil Side Effects on Liver
This topic is pretty much intriguing, as it made some headlines.
Most articles that are against CBD oil usage rely on a mice study. Having been exposed to high CBD doses, they developed hepatotoxicity.
However, what is usually omitted from catchy headlines is the fact that CBD was given in high doses. For example, the doses equaled what would be three and ten times bigger doses than the recommended one for Epidiolex.
Essentially, Epidiolex is pure CBD oil. It does come with a label warning about CBD hemp oil side effects, saying it should be used with caution if one is taking liver meds. Still, taking a dosage three times bigger is worrying no matter which medicine we are talking about.
To sum up, side effects are possible, but they will occur only with extremely high doses if your liver is healthy.
Headaches and Migraines
When buying CBD oil of some kind, these CBD oil side effects may be listed on the label. In reality, the chances of CBD provoking headaches are very low.
According to one study, CBD does not cause headaches or migraines. On the contrary, it is recommended as a cure.
The cause of headaches may have more to do with any substances or solvents added to the oil. Given that not all CBD brands are reliable, sometimes a simple change of CBD brand will end the pain.
With CBD, you never know. Your body may develop tolerance to CBD effects after some time. This usually happens if your CBD oil contains THC.
In contrast, CBD is also known to cause reverse tolerance. This means you will need a smaller dose after using CBD for a long time.
To be safe, monitor your doses and reactions.
Low Blood Pressure
The reason for lowering blood pressure could be that CBD may act as a blood thinner. If you’re already on blood-thinning meds, the side effects of CBD oil can become very dangerous.
For example, even though CBD helps post-surgical pain and recovery, you shouldn’t be taking it one week before the operation.
CBD dilates blood vessels and is an excellent aid in preventing thrombosis or the formation of blood clots. But if you’re already using blood thinners, always consult with your doctor before you start experimenting with CBD.
CBD Oil Side Effects on Heart Palpitations
CBD could potentially help people with arrhythmia due to its anti-inflammatory properties, and many studies confirm this statement.
What’s more, CBD doesn’t have serious side effects when it comes to heart palpitations. However, its interaction with other arrhythmia medications can be potentially dangerous.
For example, CBD can interact with warfarin, nitrates, certain statins, beta-blockers, and calcium channel blockers. Therefore, it’s essential to consult with your doctor before trying anything on your own.
What Are the Side Effects of CBD Oil If You Are Allergic?
A cannabis allergy is a real thing. It manifests similarly to any other pollen allergy — runny nose, sneezing, rash, or itchy skin.
The allergy may be provoked by airborne allergens, handling the plant (people working in the industry are especially at risk), or even by eating some delicious edibles. Truth be told, CBD gummies’ side effects usually come as the consequence of overdosing on them, which is even more worrying if you are allergic to CBD.
While you could have a mild allergy to cannabis, it could make other allergies stronger, particularly food allergies.
If you are taking CBD oil for the first time, beware of these CBD oil side effects — dry cough, itchy eyes, sore throat, dry skin, blisters, hives, or watery eyes. Should you experience any of these, you may be having an allergic reaction to CBD oil.
CBD Oil Interactions with Other Drugs
Admittedly, the list is quite lengthy. We already mentioned some precautions when we discussed blood thinners and liver meds. Here is what to pay special attention to if you’re using CBD with other drugs.
It will interact with the following, so we strongly advise you against using CBD with:
- Clobazam (Onfi), and
CBD may interact with:
- Topiramate (Topamax)
- Sedative medications (CNS depressants), such as Nembutal, Luminal, Seconal, Duragesic, Sublimaze, morphine, Diprivan, Pentothal, and others.
- Rufinamide (Banzel).
Side effects of CBD hemp oil can also manifest if you use:
- Medications that increase/decrease the breakdown of other drugs by the liver:
Tagamet, Luvox, Prilosec, Ticlid, Topamax, Tegretol, Dilantin, Mycobutin, etc.
- Medications that decrease the breakdown of other drugs in the liver, such as:
Cordarone, Fortovase, Invirase, E-Mycin, Erythrocin, Cardizem, etc.
- Medications changed by the liver:
Endometrin, Prometrium, Adalat CC, Procardia XL, Sandimmune, Xanax, Norvasc, Biaxin, Sandimmune, erythromycin, Mevacor, Nizoral, Sporanox, Allegra, Halcion, Calan, Isoptin, and many others.
- Eslicarbazepine (Aptiom).
Does CBD Oil Have Side Effects in Pregnancy?
Short answer — nobody knows. The American College of Obstetricians and Gynecologists (ACOG) advises pregnant women against using cannabis in all its forms, CBD oil included.
So far, research on CBD oil dangers during pregnancy hasn’t been conducted. The existing studies all relied on cases when mothers-to-be were regular cannabis consumers.
They showed that smoking weed or eating cannabis during pregnancy is dangerous for the baby and may even cause stillbirth.
However, there is no evidence whatsoever that the use of CBD oil could cause the same consequences.
More Dangers of Using CBD Oil
This section has nothing to do with how your body processes CBD but rather with the side effects of CBD. To be more precise, it deals with whether or not you got what you paid for.
Namely, CBD oil regulations are far from picture-perfect. Unless you are buying from a reliable source, you may experience some hardships.
Here are a couple of reasons which may repel you from consuming cannabidiol.
- FDA — CBD oil is not FDA regulated. It isn’t even listed as an FDA-approved dietary supplement. Why? Most probably, because cannabis is still listed as a Schedule 1 drug. Hence, it’s a bit challenging to do the paperwork for something similar to heroin (which belongs to Schedule 1 too).
- Harmful substances — Another substance can sometimes be blamed for the negative side effects of CBD oil, given that there are lots of CBD oil-infused products on the market. Even if CBD oil is of perfect quality, it can be mixed with not-so-good ingredients.
In addition, less reputable companies may treat the land and plants with poisonous pesticides to have a higher yield. That’s why we always look at third party lab tests.
- Insufficient amount of CBD — Some CBD oils can have less CBD than it says on the label (and more carrier oil). Even worse, if you change the product but keep the dosage, you could overdose and experience all the negative side effects of CBD.
- Traces of THC — Some pure CBD oils can contain THC (even though they don’t have to). This is especially dangerous if pure CBD oil is recommended for a child because THC can severely affect the young brain.
In addition to that, THC can make you positive on a drug test as it lingers in your system for a long time. Not all drug tests can discover THC, though.
- Type of use — Interaction with other medications and similar side effects depends on how exactly you are taking your recommended dose. CBD lotions or creams shouldn’t provide you with high doses of CBD, for instance.
As for edibles, the adverse effects are less intense than vaping or smoking.
CBD Oil Side Effects Summary
Like every other drug, even the “magical” CBD oil can leave you with adverse side effects. Therefore you must always consult your doctor before taking any form of CBD oil.
To avoid any potential side effects, make sure you:
- Always consult your doctor before taking any form of CBD oil.
- Buy the oil only from reputable suppliers. The same applies if you decide to make your own CBD oil. Always use the best ingredients.
- Stick to the recommended dose. The majority of issues are connected with overdosing.
- Bear in mind how you take CBD oil — via CBD pills, oil, tincture, cream, edibles, or patches
- Monitor your body and the results you get.
We hope we managed to explain all there is about CBD and its side effects and that you can enjoy its advantages without any dangers to your health.
Is taking CBD every day bad for you?
Generally, CBD is considered safe. However, cannabidiol is not water. Every body is different and little research has been completed in order for CBD to be declared safe for everyday usage without any breaks.
CBD is most known for helping with:
- Reducing epilepsy seizures
- Reducing pain and inflammation
However, when it comes to dosage, consult with your doctor, especially if you’re taking other medications.
Can you have a bad reaction to CBD oil?
Yes, experiencing a bad reaction to CBD is possible. Although most people can tolerate CBD, using it can cause some side effects. The most common are the following:
- Appetite boost or loss
- Dry mouth and sore throat
- Low blood pressure
CBD can also cause tolerance and reverse tolerance. In other words, your body can develop a tolerance to the substance (if there’s THC in the oil). At the same time, if your body develops reverse tolerance, you’ll need smaller doses of CBD.
What drugs should not be taken with CBD?
CBD can interact with other drugs, which can cause various side effects. You should be cautious when mixing CBD with:
- Clobazam (Onfi)
- Topiramate (Topamax)
- Sedative medications (Nembutal, Luminal, Seconal, Duragesic, Sublimaze, morphine, Diprivan, Pentothal)
- Rufinamide (Banzel)
- Medications that increase/decrease the breakdown of other drugs by the liver
- Medications that decrease the breakdown of other drugs in the liver
- Medications changed by the liver
The mentioned drugs can cause severe CBD oil side effects when mixed together.