CBD Research: An Insight Into the Top Studies and Trials
We often hear about the large number of symptoms that CBD can be used for – pain, anxiety, depression, ADHD, diabetes, and the list goes on. Our first instinct is to wonder where the evidence is? Thankfully, it exists – there are plenty of sources and studies spread throughout the web. We’ve curated this compilation of studies, trials, and other CBD research to consolidate the best research into one place! Rather than scour the internet for this information, you can find different studies for various symptoms – all in one article.
Symptoms & Conditions
If you’re interested in research regarding the benefits of CBD for the following symptoms or conditions, you can read about them in this article:
- Parkinson’s Disease
- Research on Pets
What Is CBD?
Let’s start off with a brief intro about CBD. This is one of the many phytocannabinoids (aka molecules made naturally by plants) that occurs in cannabis. Unlike THC, another common phytocannabinoid, CBD, doesn’t get you high. It targets different receptors in the body. As you might guess, marijuana contains high amounts of THC.
CBD can be extracted from marijuana, but it would have too much THC to be considered legal. This is why it’s extracted from a different type of cannabis – industrial hemp. Bred specifically for extracting CBD, this strain of cannabis contains a high amount of CBD and a very low amount of THC.
Why has this substance become so popular? Because there are so many CBD benefits – it’s hard to even count them all! It has been used for centuries as natural medicine.
Is CBD Legal?
Since CBD is related to marijuana, many people have been worried and confused about the legality. The answer is yes – it is now legal under certain circumstances. The Farm Bill was passed in 2018, making CBD legal in the USA as long as it contains 0.03% or less THC and is extracted from hemp.
CBD Research 2019
When CBD enters the bloodstream, it targets endocannabinoid receptors located in the brain. This is why it offers so many neurological benefits! These receptors are located throughout the body as well, giving it an even larger reach.
The connection between CBD and neurological benefits are huge, and researchers have only just begun discovering them.
- This CBD research article shares a compilation of information about recent findings related to neurological benefits. It includes benefits for Parkinson’s disease, multiple sclerosis, neuropathic pain, epilepsy, mood disorders (such as schizophrenia), anxiety, depression, addiction, and even more.
Keep scrolling for more articles and studies!
Hemp oil for pain is one of the top symptoms that CBD is used for. It works for chronic pain, targeted pain, various types of arthritis pain, multiple sclerosis, even menstrual cramps!
The following studies analyze how cannabidiol targets pain:
- Cannabinol reduces inflammation and pain-related symptoms in a rat model of arthritis.
- Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 receptors.
CBD oil for anxiety is another one of the most common uses. Many people have tried it out and report a significant decrease in anxiety! Evidence shows that CBD disrupts fear memories.
- Cannabidiol (CBD) disrupts the consolidation of specific and generalized fear memories.
- This study involves both sleep and anxiety.
Epilepsy is a disorder of recurring seizures that an estimated 50 million people worldwide suffer from. CBD has shown huge promise for this condition – it’s already been approved for use in the form of prescription medication after a number of reliable research trials and CBD oil studies confirmed its benefits. This drug is called Epidiolex, and is the first prescription medication that uses cannabidiol!
- This article compiles information from a variety of CBD studies relating to epilepsy. Each of them shows positive results in reducing seizures.
- Another large study tested the use of CBD on 120 children and young adults with Dravet syndrome (a severe form of epilepsy in children). The results showed that the median frequency of convulsive seizures per month drastically decreased from 12.4 to 5.9 with cannabidiol.
When it comes to CBD oil, ADHD research is another promising topic. Although studies are limited, they bring hope for the future. The medication given to children and adults with ADHD (such as Adderall) can be addictive, not to mention the harmful side effects.
There are plenty of CBD cancer studies that show incredible potential. At the very least, CBD can help with cancer-related pain. However, scientists have searched even deeper to find that CBD shows anti-tumor properties!
The new CBD oil for cancer research is promising and much more needs to be done, but these first findings definitely bring hope for the future. It’s even being considered as a cancer preventative medicine.
There is less CBD oil research in this area, but what researchers have found is very positive for autism statistics. They’ve found a potential link between autism and the CB2 receptors within the endocannabinoid system. This is one of the receptors that CBD and THC act upon, which sparks the consideration that these substances may be useful for autism symptoms.
- In this case study, an autistic child given THC for six months reported significant reductions in symptoms of autism. One of the symptoms – inappropriate speech – was even eliminated completely!
Pennsylvania and Minnesota are currently the only states that have approved medical marijuana for autism. Even so, CBD is legal in all 50 states and is more easily accessible for many.
CBD has been studied for nicotine or cigarette addiction. It’s helped many people quit smoking and helps curb their cravings!
- The results in this study showed a 40% reduction in the number of cigarettes smoked when a group was given a CBD inhaler, with a trend indicating a reduction after follow-up. It also shared that animal studies have shown the possible effects of CBD on opioid and psychostimulant addiction.
- opioid and psychostimulant addiction.
Furthermore, addictions statistics confirm CBD is recommendable for ending heroin and opioid addiction.
Alzheimer’s is arguably one of the worst diseases out there. Although there haven’t been many CBD trials relating to Alzheimer’s yet, it shows the possibility to be used as treatment. According to researchers at California’s Salk Institute, their 2017 study has found evidence that cannabinoids such as CBD could help reduce dementia.
A few studies strongly suggest that it may have great therapeutic potential in the treatment of diabetes (and perhaps cardiovascular disorders) by reducing oxidative/nitrative stress, inflammation, cell death, and fibrosis.
Gastrointestinal Issues (IBS)
Another subject of research on CBD oil is for gastrointestinal issues, most commonly being IBS. These range from enteric infections and inflammatory conditions to disorders of motility, emesis, and abdominal pain. One of the most common issues is IBS, aka irritable bowel syndrome.
- Cannabinoids and gastrointestinal motility: animal and human studies.
- The digestive track and cannabidiol.
There has been a little research for asthma as well. Although most research is done on animals like guinea pigs, cannabinoids have shown to reduce asthma-like reactions. Even with the lack of research, this is an easy symptom to target if you have asthma – simply try CBD and see if it helps reduce reactions.
- The activation of cannabinoid receptors inhibits antigen-induced asthma reactions in guinea pigs.
- Cannabinol treatment for asthma in an animal model.
Cannabinoids may also help to manage Parkinson’s disease symptoms and slow the progression.
- In a 2004 survey of cannabis use among patients at the Prague Movement Disorder Centre in the Czech Republic, 45 percent of respondents reported improvement in PD motor symptoms.
CBD market research shows many people use cannabidiol to help their pets, but is it as healthy and safe as it is for humans? How trustworthy is the CBD research in this category? For humans, many people worry about the long-term health risks that may be unknown. With pets, this is less of a concern since their lives are much shorter.
Because of this, CBD makes sense for pets who are at hard stages in their lives. For example – cats or dogs that can’t walk, experience cancer pain or other symptoms, have arthritis, severe anxiety, or other symptoms of old age. It’s also a good option if they experience extreme aggression (to the point where they harm others).
Check out interesting CBD for pets research!
The Bottom Line
This is a lot of information to take in. The bottom line is, no matter what your symptoms are, CBD is a natural medicine that is worth trying out. It’s not addictive and has shown no severe side effects, only small things (like drowsiness and nausea). CBD research shows that, even in very high doses, you can’t overdose. There are plenty of benefits of CBD that research supports.
Are there any side effects of CBD?
There are only a few mild side effects that you might experience when taking too much CBD oil – diarrhea, drowsiness, nausea, changes in appetite, and dizziness are the worst. The most common is drowsiness, but many people have found this to be a good thing if they have trouble sleeping!
Is CBD a neuroprotectant?
Yes! Since it acts on receptors located in the brain, it has plenty of neurological benefits. It shows great possibilities for this field! Skip up to the first section to learn more and see research about neurological benefits.
Does CBD oil get you high?
No! As we mentioned above, it’s antipsychotic – meaning it doesn’t get you high. It contains very little THC, which is the substance that does get you high (the legal requirement is 0.03% THC or less). You can also purchase completely THC free CBD oil (known as isolate) or broad spectrum.
Is CBD oil a blood thinner?
CBD has been found to have natural blood-thinning properties, which is why doctors advise against taking it with medications that warn against eating grapefruit. CBD has many of the same properties as grapefruit.
Is CBD a drug?
Technically, no – CBD hasn’t been officially labeled by the FDA as a drug or medicine. It’s sold as a supplement. However, it has plenty of medicinal uses and benefits as shown from the research above. It has recently been approved by the FDA in a prescription medication for epilepsy!
What types of pain does CBD oil work for?
It should work for all types! You can use CBD oil for joint pain, cancer-related pain, menstrual pain, IBS pain, and more. Some people with chronic and severe pain need higher doses, though.
How does CBD oil make you feel?
Unlike marijuana, CBD won’t give you a high or euphoria. The feelings are commonly described as relief, relaxation, or focus. It all depends on what you’re using it for. If you use CBD oil for pain, you will feel relief.
There are plenty of people who have used marijuana for pain or anxiety, and the discovery of CBD is a miracle. It gives the much needed relief without negative side effects. They can use it in their daily lives without having to change anything.
Are there any CBD pregnancy studies?
There is limited research on the side effects of taking CBD while pregnant. If you’re considering this, it may be safer to avoid it until there is conclusive evidence. The possible effects on the fetus are unknown. Studies have shown that using marijuana during pregnancy can lead to smaller babies with lower birth weight, as well as other side effects.
How do I pick the best CBD oil?
It seems like there are so many brands out there that sell the same products. It’s hard to tell the difference! However, there are definitely things to look out for if you want quality. This includes the origin of the CBD, how it’s extracted, full-spectrum compared to isolate, and more.
Is CBD safe for children?
Since CBD oil research shows very little side effects, it can also be a good choice for children with various symptoms. It’s not illegal for kids, so the decision is completely up to the parents. It’s a great alternative if you’re considering prescription medicines for your child (such as anxiety or depression medicine). These have so many possible side effects, whereas CBD is very safe.
Is CBD addictive?
Nope! No matter how much you consume (even multiple times per day), there is no risk of addiction to CBD oil. It’s safe and has excellent tolerability in humans.
What other symptoms does CBD help with?
Aside from our list, there are even more symptoms and issues that CBD can help with! These include high blood pressure, pain during sex, sexual arousal, skin issues like acne or eczema, and more. There aren’t as many CBD clinical trials and studies to support these, which is why we didn’t include them. However, people have tried it for these symptoms and reported great results.